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Updated: May 13, 2026

Isolating Nasal Olfactory Stem Cells from Rodents or Humans
09:19

Isolating Nasal Olfactory Stem Cells from Rodents or Humans

Published on: August 22, 2011

嗅覚センサーニューロンからクローン化したマウス

Kevin Eggan1, Kristin Baldwin, Michael Tackett

  • 1Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

Nature
|March 3, 2004
PubMed
まとめ

科学者たちは,成熟した嗅覚感覚神経細胞の核を用いてマウスをクローンした. これは,末端分化ニューロンがクローン化に成功するために再プログラムされることができることを示しており,これは発達生物学における重要な進歩である.

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Whole Mount Labeling of Cilia in the Main Olfactory System of Mice08:42

Whole Mount Labeling of Cilia in the Main Olfactory System of Mice

Published on: December 27, 2014

Perforated Patch-clamp Recording of Mouse Olfactory Sensory Neurons in Intact Neuroepithelium: Functional Analysis of Neurons Expressing an Identified Odorant Receptor10:16

Perforated Patch-clamp Recording of Mouse Olfactory Sensory Neurons in Intact Neuroepithelium: Functional Analysis of Neurons Expressing an Identified Odorant Receptor

Published on: July 13, 2015

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Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...