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Updated: Jul 20, 2026

Methods to Identify the NMR Resonances of the 13C-Dimethyl N-terminal Amine on Reductively Methylated Proteins
13:59

Methods to Identify the NMR Resonances of the 13C-Dimethyl N-terminal Amine on Reductively Methylated Proteins

Published on: December 12, 2013

膜輸送タンパク質に対する基板親和性は,13C交差極化魔法の角度回転核磁共振スペクトロスコーピーによって決定される

Simon G Patching1, Adrian R Brough, Richard B Herbert

  • 1Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, Sackville Street, Post Office Box 88, Manchester M60 1QD, United Kingdom.

Journal of the American Chemical Society
|March 12, 2004
PubMed
まとめ

新しい固体NMR方法は,NupCやGusBのような膜輸送タンパク質に対する基板結合を正確に測定します. これらの技術は,結合親和性を定量化し,様々な膜タンパク質の薬剤および抗生物質の開発を支援します.

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