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Updated: Aug 25, 2026

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
10:51

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

Published on: November 15, 2013

RXRヘテロダイマーにおけるアロステルリガンド活性化の構造的決定因子

Andrew I Shulman1, Christopher Larson, David J Mangelsdorf

  • 1Howard Hughes Medical Institute, Department of Pharmacology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.

Cell
|March 16, 2004
PubMed
まとめ

核受容体は,遺伝子調節のためにアロステリック通信を使用します. この研究は,これらの受容体内のエネルギーネットワークを特定し,異なるリガンド信号を区別する方法を明らかにします.

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Structure-Guided Design and Development of Novel Cyclophilin A Inhibitors and Ganoderiol-F Derivatives: An In-Silico Approach10:01

Structure-Guided Design and Development of Novel Cyclophilin A Inhibitors and Ganoderiol-F Derivatives: An In-Silico Approach

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