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Updated: May 6, 2026

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gp91phoxを含むNADPH酸化酵素は,腎血管高血圧における内皮機能不全を媒介する

O Jung1, J G Schreiber, H Geiger

  • 1Institut für Kardiovaskuläre Physiologie, Klinikum der J.W. Goethe-Universität, Frankfurt am Main, Germany.

Circulation
|March 24, 2004
PubMed
まとめ

内皮のgp91phox NADPH酸化酵素は,スーパーオキシドを生成し,酸化窒素の可用性を低下させ,腎血管高血圧における内皮機能不全を引き起こします. gp91phoxをノックアウトすることで,この機能不全を防ぐことができます.

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