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Updated: Jul 18, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
06:34

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インドールと非活性化オレフィンとのプラチナ触媒による分子内アルキル化

Cong Liu1, Xiaoqing Han, Xiang Wang

  • 1P. M. Gross Chemical Laboratory, Duke University, Durham, North Carolina 27708-0346, USA.

Journal of the American Chemical Society
|March 25, 2004
PubMed
まとめ

プラチナ触媒は,2-アルケニルインドールからカルバゾール誘導体の効率的な合成を可能にします. この方法は,様々な置換を許容し,保護されていないインドルおよび関連するヘテロサイクルに適用できる多用途です.

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Acid Halides to Carboxylic Acids: Hydrolysis01:01

Acid Halides to Carboxylic Acids: Hydrolysis

Hydrolysis of acid halides is a nucleophilic acyl substitution reaction in which acid halides react with water to give carboxylic acids. The reaction occurs readily and does not require acid or a base catalyst.
As shown below, the mechanism involves a nucleophilic attack by water at the carbonyl carbon to form a tetrahedral intermediate. This is followed by the reformation of the carbon–oxygen π bond along with the departure of a halide ion. A final proton transfer step yields carboxylic acid...
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Nitriles to Ketones: Grignard Reaction

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The mechanism begins with a nucleophilic attack by the Grignard reagent...
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Reactions of Carboxylic Acids: Introduction

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