関連する実験動画
Updated: Jul 13, 2026
06:53
Probing Myosin Ensemble Mechanics in Actin Filament Bundles Using Optical Tweezers
Published on: May 4, 2022
ミオシン遺伝子変異は,ヒトの系統における解剖学的変化と相関する
Hansell H Stedman1, Benjamin W Kozyak, Anthony Nelson
1Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. hstedman@mail.med.upenn.edu
Nature
|March 26, 2004
まとめ
遺伝子の突然変異により,ヒトの祖先のミオシン重鎖 (MYH) が不活性化され,噛む筋肉が小さくなった. このプロテオミクスの変化は約240万年前に発生し,初期のホモとチンパンジーを区別しました.
科学分野:
- 進化生物学の進化生物学について
- パレオプロテオミクスの学問
- 人間の起源 人類の起源
背景:
- 噛む筋肉は類人猿や初期のヒト類で強力で,ホモの小さな筋肉とは対照的です.
- ホミニドの器系は,チンパンジーのような祖先から,人間の脳の膨張と一致して,グラシライゼーションへと進化した.
関連する概念動画
01:39Mutations
Overview
01:39Mutations
Overview
02:05Gene Evolution - Fast or Slow?
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
01:15Overview of Myosin Structure and Function
Myosins are a family of molecular motor proteins, first identified in the skeletal muscles, where they are responsible for muscle contraction. Along with their role in muscle contraction, these proteins also play a role in the intracellular transport of molecules and vesicles. There are twenty-four classes of myosins based on their domain sequence and organization. Of the twenty-four, six classes (Myosin I, Myosin II, Myosin V, Myosin VI, Myosin VII, and Myosin X) have been well characterized.
01:35Mutations
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
02:05Gene Evolution - Fast or Slow?
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...