src23,c-abl

M Overduin1, C B Rios, B J Mayer

  • 1Laboratories of The Rockefeller University New York, New York 10021.

Cell
|August 21, 1992
PubMed
まとめ

この研究では,abl SH2ドメインの3D構造を決定し,そのコンパクトな球状の形状と,フォスフォチロジン結合に関与する主要な残基を明らかにしました. この発見は,SH2ドメインが標的タンパク質を認識する方法を理解するのに役立ちます.

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