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関連する概念動画

Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...

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関連する実験動画

Updated: Jul 6, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Published on: January 22, 2018

臓がんは,臓がんである.

Donghui Li1, Keping Xie, Robert Wolff

  • 1Department of Gastrointestinal Medical Oncology, University of Texas, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 426, Houston, TX 77030, USA.

Lancet (London, England)
|March 31, 2004
PubMed
まとめ

臓がんは,治療の選択肢が限られ,死亡率が高く,予後が悪い. その分子生物学を理解するうえでの進歩は,より効果的な治療法を開発するための希望を提供します.

科学分野:

  • 腫瘍学 腫瘍学
  • 分子生物学は分子生物学である.
  • がん研究 がん研究

背景:

  • 臓がんは,健康上の大きな課題であり,その結果が悪い.
  • 従来の治療はほとんど効果がなく,ほとんどの患者は致命的な転移を発症します.
  • 主要な危険因子には,喫煙,年齢,遺伝的傾向が含まれるが,主な原因は不明である.

研究 の 目的:

  • 臓がんの病原性に関する現在の理解をレビューする.
  • 既存の治療法の限界について議論する.
  • 有望な新しい治療戦略を強調する.

主な方法:

  • 分子生物学の見直し 臓がんの理解における進歩.
  • 現在の治療方法とその緩和効果の分析.
  • 新興治療アプローチの探索.

主要な成果:

  • 臓がんの病原化には,K-ras腫瘍遺伝子の変異と不活性化された腫瘍抑制遺伝子が含まれています.
  • 成長因子は,疾患の進行において重要な役割を果たします.
  • 現在の治療法では生存率が限られており,切除可能な症例では5年生存率は約20%である.

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Reprogramming Pancreatic Ductal Adenocarcinoma to Pluripotency
07:08

Reprogramming Pancreatic Ductal Adenocarcinoma to Pluripotency

Published on: February 2, 2024

関連する実験動画

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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
10:28

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker
07:47

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker

Published on: September 15, 2023

Reprogramming Pancreatic Ductal Adenocarcinoma to Pluripotency
07:08

Reprogramming Pancreatic Ductal Adenocarcinoma to Pluripotency

Published on: February 2, 2024

結論:

  • 臓がんは,現在の治療法に対して依然として抵抗性があり,新しいアプローチが必要である.
  • 術前化学放射線治療やゲムシタビンの使用拡大などの研究方法も検討されています.
  • 臓がんの分子基盤を標的とする治療戦略は,患者の改善結果を最も有望にしています.