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ヒト内皮細胞に対する炎症前作用には,C反応性タンパク質の適合的再編成が必要である

Tarek Khreiss1, Levente József, Lawrence A Potempa

  • 1Research Center, Maisonneuve-Rosemont Hospital and Department of Medicine , University of Montreal, Montreal, QC, Canada.

Circulation
|March 31, 2004
PubMed
まとめ

修飾されたC反応性タンパク質 (mCRP) は内皮細胞を活性化し,冠動脈疾患の炎症を促進します. これはp38 MAPK経路を通じて発生し,ネイティブCRPとは異なり,mCRPを重要な炎症媒介体として強調しています.

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