子どもにおける肥満に関連する血管機能不全に対する食事と運動の効果
Kam S Woo1, Ping Chook, Chung W Yu
1Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong. kamsangwoo@cuhk.edu.hk
Circulation
|April 7, 2004
まとめ
幼児の肥満は動脈機能不全を引き起こします. ダイエットと運動の介入は,この血管機能不全を逆転させることができ,食事と運動の組み合わせは,子供の血管の健康にとって最良の結果を示しています.
科学分野:
- ペディアトリック・カルディオロジー
- 血管生物学 血管生物学とは
- 予防医学は,予防的な医療です.
背景:
- 子どもの肥満は,拡大する流行病です.
- 子供の肥満は,早期の動脈機能不全と加厚に関連しています.
- これらの血管の変化は,動脈硬化症の前兆である.
研究 の 目的:
- ライフスタイルの介入によって,肥満に関連した動脈機能不全と小動脈内側介質の加厚を子どもで逆転させることができるかどうかを評価する.
- ダイエットのみの効果と,ダイエットと運動の効果を比較する.
主な方法:
- 82人の肥満児 (9~12歳) は,ランダムに6週間のダイエットのみ,または6週間のダイエットと監督された運動,その後1年間に分けられた.
- 測定された主なアウトカムは,腕動脈の内皮機能と,超音波による頸動脈内膜介質の厚さでした.
- 二次的なアウトカムには,腰と腰の比率,コレステロール,体脂肪含有量が含まれていました.
主要な成果:
- 両方の介入により,内皮機能が改善され,腰と腰の比率が低下し,6週間後にコレステロールが低下しました.
- ダイエットと運動は,ダイエットだけでより大きな内皮機能の改善をもたらしました.
- 1年後に,運動を継続した子どもでは,血管の健康と体調の持続的な改善が観察されました.
結論:
- 肥満に関連する小児の血管機能不全は,ライフスタイルの変化で回復する.
- ダイエットと運動を組み合わせた介入は特に効果的です.
- ダイエットと運動の継続的な遵守は,子どもたちの血管の健康に長期的な利点をもたらします.
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