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Updated: Jul 6, 2026

Methods to Identify the NMR Resonances of the 13C-Dimethyl N-terminal Amine on Reductively Methylated Proteins
13:59

Methods to Identify the NMR Resonances of the 13C-Dimethyl N-terminal Amine on Reductively Methylated Proteins

Published on: December 12, 2013

ヒトの炭酸アンヒドラゼの固体亜鉛型NMRスペクトロスコーピー:酵素機構への影響

Andrew S Lipton1, Robert W Heck, Paul D Ellis

  • 1Macromolecular Structure & Dynamics Directorate, W. R. Wiley Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99352, USA.

Journal of the American Chemical Society
|April 9, 2004
PubMed
まとめ

人間の炭酸アンヒドラゼ (CAII) の固体状態のNMRは,水酸化物ではなく,広範囲のpH範囲で亜鉛に結合していることを明らかにしています. この発見は,CAIIの受け入れられた触媒メカニズムに異議を唱える.

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