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IkappaBキナーゼ-アルファは表皮に作用し,骨格と頭蓋骨の顔面形態変異を制御する

Alok K Sil1, Shin Maeda, Yuji Sano

  • 1Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0636, USA.

Nature
|April 9, 2004
PubMed
まとめ

IkappaBキナーゼ-アルファ (IKK-アルファ) は,表皮の分化に不可欠であり,これは正常な骨格および頭蓋骨の発達に不可欠です. エピダーミスのIKK-alphaの回復は,これらの発達上の欠陥を修正します.

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