関連する実験動画
Updated: Jul 15, 2026

07:15
Invasion of Human Cells by a Bacterial Pathogen
Published on: March 21, 2011
古代の侵略:エンドシンビオンから臓器細胞まで
Sabrina D Dyall1, Mark T Brown, Patricia J Johnson
1Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, 405 Hilgard Avenue, Los Angeles, CA 90095-1489, USA.
まとめ
ユーカリオット細胞の進化には,ユーバクテリアがミトコンドリアとプラスティドになり,必要不可欠な細胞工場を作り出す古代の共生イベントが含まれていました. これらのエンドシンビオントは,生存と宿主細胞への統合のための複雑なメカニズムを進化させた.
科学分野:
- 進化生物学の進化生物学について
- 細胞生物学 細胞生物学
- ゲノミクスゲノミクスとは
背景:
- ミトコンドリアとプラスティドは10億年以上前にエウバクテリアのエンドシンビオシスから発生した.
- これらの臓器細胞は,真核細胞の生物エネルギーおよび生物合成機能に不可欠です.
研究 の 目的:
- エンドシンビオントの進化をオーガネルへと導く分子現象を探求する.
- 臓器進化の過程におけるゲノムと機能の変容を理解する.
主な方法:
- 地化学的分析が行われる.
- 分子フィロゲーニシスは,分子フィロゲーニシスである.
- 細胞生物学調査 細胞生物学調査
主要な成果:
- エンドシンビオントは,オルガネルになった後,ゲノムの重要な部分を失いました.
- 臓器細胞の生体生成と代謝物質の交換のための複雑なメカニズムが進化した.
- シンビオントは宿主特性を獲得し,ユーバクテリアのアイデンティティを低下させた.
結論:
- エンドシンビオントの統合は,真核生物の進化における重要なステップを表しています.
- 臓器の多様性は,まだ発見されていない複雑な進化の歴史を反映しています.
関連する概念動画
Types of Genetic Transfer Between Organisms
Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
Endocytosis
Eukaryotic cells acquire nutrients for growth and proliferation. Nutrients and other molecules that require degradation are internalized from the extracellular space by a process called endocytosis. The term ‘endocytosis' was first coined by Christian de Duve in 1963.
Endocytosis always begins with the plasma membrane enclosing an incoming molecule to form a transport vesicle which, in some cases, can be coated with a protein called ‘clathrin.' Endocytosed material is either sorted through...
Endocytosis always begins with the plasma membrane enclosing an incoming molecule to form a transport vesicle which, in some cases, can be coated with a protein called ‘clathrin.' Endocytosed material is either sorted through...
Types of Genetic Transfer Between Organisms
Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
Infection
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Microbial Interactions: Parasitism
Parasitism is a form of microbial interaction in which parasitic microbes exploit a host organism for nutrients and shelter, often at the host's expense. Unlike mutualistic relationships, where both organisms benefit, parasitism benefits only the parasite and harms the host.Classification of ParasitesMicrobial parasites are broadly classified based on their location relative to the host.Ectoparasites remain on the host’s surface, such as the skin or outer tissues, drawing nutrients...
Colonisation of Pathogens
Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...

