Escherichia coliの二酸化水素葉酸還元酵素の触媒におけるトンネリングと結合運動

R Steven Sikorski1, Lin Wang, Kelli A Markham

  • 1Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.

まとめ

ディヒドロフォラート還元酵素の触媒における水素トンネリングが調査されました. この研究は,結合運動ではなく,環境結合トンネリングの証拠を発見し,安定状態前の反応中に触媒へのコミットメントを示唆した.

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