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Updated: Jul 21, 2026

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アルファ・ターン・ミミティクス:周期性メタロペンタペプチドモジュールからなる短いペプチドアルファヘリックス

Michael J Kelso1, Renée L Beyer, Huy N Hoang

  • 1Centre for Drug Design and Development, Institute for Molecular Bioscience, University of Queensland, Brisbane, Qld 4072, Australia.

Journal of the American Chemical Society
|April 15, 2004
PubMed
まとめ

この研究では,短くて構造のないペプチドをサイクルメタルペプチドモジュールを用いてアルファヘリックスに安定させています. これらの新しいペプチド金属複合体は,タンパク質の構造を模倣し,タンパク質の研究と薬剤設計のための新しい道を開きます.

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