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Updated: May 8, 2026

Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
11:10

Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice

Published on: November 16, 2011

肥満の超レプチネミアは,カロリー過剰の肥満調節剤である

Roger H Unger1

  • 1Touchstone Center for Diabetes Research, Department of Internal Medicine, UT Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Y8.212, Dallas, TX 75390, USA.

Cell
|April 16, 2004
PubMed
まとめ

レプチンとアノレキシゲン薬は,下体内のAMP活性化タンパク質キナーゼ (AMPK) を無効化し,マロニルCoAを増加させることで食欲を低下させます. この研究では,AMPの生物学,マロニル-CoA生成,およびレプチンに関する研究が行われています.

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