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Updated: Apr 15, 2026

Generation of Human Alloantigen-specific T Cells from Peripheral Blood
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Generation of Human Alloantigen-specific T Cells from Peripheral Blood

Published on: November 21, 2014

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免疫不全時のT細胞の恒常的な膨張は,自己免疫を生成する

Cecile King1, Alex Ilic, Kersten Koelsch

  • 1Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|April 16, 2004
PubMed
まとめ

減少したT細胞数 (リンフォペニア) と補償増殖は,自己免疫疾患を引き起こす可能性があります. サイトカインIL-21に対する反応の増加は,T細胞の周回を悪化させ,自己免疫を引き起こす.

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