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Updated: Jul 15, 2026

Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model
08:53

Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model

Published on: January 1, 2017

ITAMモチーフによって媒介されるコストシグナルが,骨の恒常性のためにRANKLと協力する

Takako Koga1, Masanori Inui, Kazuya Inoue

  • 1Department of Immunology, Graduate School of Medicine and Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan.

Nature
|April 16, 2004
PubMed
まとめ

免疫系アダプターであるFc受容体共通ガンマサブユニット (FcRgamma) とDNAX活性化タンパク質 (DAP) 12は,骨の健康に極めて重要です. 欠乏すると,骨格細胞の分化が損なわれ,骨格の恒常性を維持する上で重要な役割が強調される.

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A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation

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