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Updated: Jul 30, 2026

Artificial Antigen Presenting Cell (aAPC) Mediated Activation and Expansion of Natural Killer T Cells
13:18

Artificial Antigen Presenting Cell (aAPC) Mediated Activation and Expansion of Natural Killer T Cells

Published on: December 29, 2012

AP-1によるトランザクティベーションは,T細胞のクローナルアナーギーの分子標的である

S M Kang1, B Beverly, A C Tran

  • 1Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.

Science (New York, N.Y.)
|August 21, 1992
PubMed
まとめ

トレランスの状態であるTリンパ球アナージー (T lymphocyte anergy) は,AP-1の活性が低下したため,インタールイキン-2遺伝子転写を損なう. インターリューキン-2治療は,このアナーギーを逆転させ,T細胞の反応性を回復させることができます.

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