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Updated: Jul 18, 2026

Axon Stretch Growth: The Mechanotransduction of Neuronal Growth
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成長因子を細胞外空間に流し込むことによるメカノトランスデュークション

Daniel J Tschumperlin1, Guohao Dai, Ivan V Maly

  • 1Physiology Program, Department of Environmental Health, Harvard School of Public Health, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|April 23, 2004
PubMed
まとめ

物理的な力は,上皮細胞間の空間を縮小し,局所的な成長因子濃度を増やすことで,細胞シグナリングを誘発します. このオトクリンメカニズムは,細胞内力に依存する経路なしに,表皮成長因子受容体シグナル伝達を活性化します.

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