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Updated: May 11, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

Rab5は,受容体チロシンキナーゼによるアクチン改造に関与するシグナル伝達GTPaseである

Letizia Lanzetti1, Andrea Palamidessi, Liliana Areces

  • 1Istituto Europeo di Oncologia, Via Ripamonti 435, 20141 Milan, Italy.

Nature
|May 21, 2004
PubMed
まとめ

Rab5 GTPaseは,細胞内トラフィックとアクチンリモデリングを制御する. そのエフェクターであるRN-treは,マクロピノサイトーシスにとって極めて重要であり,Rab5をアクチン細胞骨格と結びつけ,重要な信号伝達経路を明らかにする.

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Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates11:28

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates

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Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay13:51

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay

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