関連する実験動画

Updated: Jul 15, 2026

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells
09:49

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells

Published on: August 13, 2010

抗体クラスの切り替えの転写プログラムには,抑制器Bach2が関与しています

Akihiko Muto1, Satoshi Tashiro, Osamu Nakajima

  • 1Department of Biomedical Chemistry and Leukemia Program Project, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima 734-8551, Japan.

Nature
|May 21, 2004
PubMed
まとめ

バッハ2は,クラス・スイッチ・リコンビネーション (CSR) とソマティック・ハイパーミューテーション (SHM) による抗体多様化に不可欠である. 欠乏すると,IgG反応が阻害され,ユーモラル免疫におけるIgGの役割が強調される.

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Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation11:06

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Published on: September 20, 2017

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches09:35

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches

Published on: April 20, 2021

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