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Updated: Jul 19, 2026

Implementation of a Permeable Membrane Insert-based Infection System to Study the Effects of Secreted Bacterial Toxins on Mammalian Host Cells
09:25

Implementation of a Permeable Membrane Insert-based Infection System to Study the Effects of Secreted Bacterial Toxins on Mammalian Host Cells

Published on: August 19, 2016

病原性ミコバクテリアからのタンパク質キナーゼGは,マクロファージ内の生存を促進します

Anne Walburger1, Anil Koul, Giorgio Ferrari

  • 1Biozentrum, University of Basel, Klingelbergstr. 50/70, CH-4056 Basel, Switzerland.

Science (New York, N.Y.)
|May 25, 2004
PubMed
まとめ

病原性ミコバクテリアは,ライソソーム融合を阻害するタンパク質キナーゼGを分泌することで免疫細胞を回避します. このキナーゼを阻害すると,マイクロバクテリアがマクロファージ内で破壊され,新しい治療標的が提供されます.

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Development and Identification of a Novel Subpopulation of Human Neutrophil-derived Giant Phagocytes In Vitro

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