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Updated: Jun 9, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

小型のGTP結合タンパク質 rab4は,内細胞経路における早期分類イベントを制御する

P van der Sluijs1, M Hull, P Webster

  • 1Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510.

Cell
|September 4, 1992
PubMed
まとめ

Rab4タンパク質は,エンドソームの循環と流体相内細胞化を調節する. 過剰発現する野生型のRab4は,液体吸収を低下させ,トランスファーリン受容体のリサイクルを変化させ,鉄の輸送に影響を与えます.

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Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay13:51

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay

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GTPases and their Regulation02:14

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Guanine nucleotide-binding proteins (G-proteins), also known as GTPases, are a superfamily of proteins that regulate many cellular processes, such as cell signaling, vesicular transport, and the regulation of cell shape and motility. Mutation or dysfunction of these proteins can lead to disease. There are around 40,000 known G-proteins that can broadly be classified into two groups ‒  small G-proteins consisting of a single domain and large multi-domain G-proteins.
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