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Updated: May 29, 2026

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
06:52

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages

Published on: May 21, 2018

炎症性カスパス:細胞内先天免疫系と自己炎症性疾患を結びつける

Fabio Martinon1, Jürg Tschopp

  • 1Department of Biochemistry, University of Lausanne, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.

Cell
|May 28, 2004
PubMed
まとめ

カスパゼ-1のような炎症性カスパゼは,免疫反応に不可欠であり,炎症体複合体によって活性化されます. 特にNALP3/クリオピリンを含むこれらの経路の調節障害は,自己炎症性疾患につながる可能性があります.

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