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Updated: Jul 20, 2026

Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
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AKT2の変異による重度のインスリン抵抗性と糖尿病の家族

Stella George1, Justin J Rochford, Christian Wolfrum

  • 1Department of Clinical Biochemistry, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK.

Science (New York, N.Y.)
|May 29, 2004
PubMed
まとめ

AKT2遺伝子の突然変異は,重度のインスリン抵抗性や糖尿病を引き起こす. この研究は,ヒトのインスリン感受性におけるAKTシグナル伝達の重要な役割を強調し,2型糖尿病の発症に影響を与えています.

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