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Updated: May 5, 2026

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ハイパーアルドステロン症の高血圧患者の内皮に依存した流通媒介性血管拡張の障害

Mari K Nishizaka1, M Amin Zaman, Sharon A Green

  • 1Vascular Biology and Hypertension Program, University of Alabama at Birmingham, Birmingham, USA. marikn@uab.edu

Circulation
|June 3, 2004
PubMed
まとめ

アルドステロンの過剰摂取は,耐性高血圧の患者の内皮機能を損なっており,血管の膨張を減少させます. スピロノラクトンによる治療は,この機能を改善し,心臓血管疾患の潜在的な治療目標を示唆しました.

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