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関連する概念動画

Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
Taste Buds and Receptors01:20

Taste Buds and Receptors

Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
Respiratory System Abnormal Finding II: Palpation and Auscultation01:31

Respiratory System Abnormal Finding II: Palpation and Auscultation

In assessing respiratory abnormalities, palpation and auscultation are critical tools for detecting and interpreting various pathophysiological changes. These techniques provide insight into underlying disorders by evaluating tactile sensations and sounds produced by the respiratory system.
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
Auditory Perception01:17

Auditory Perception

The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the cochlea, a...
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex. This...

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Updated: Jul 11, 2026

A Wind Tunnel for Odor Mediated Insect Behavioural Assays
05:25

A Wind Tunnel for Odor Mediated Insect Behavioural Assays

Published on: November 30, 2018

周りの嗅覚プロジェクションの産後精錬

Dong-Jing Zou1, Paul Feinstein, Aimée L Rivers

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA. dz98@columbia.edu

Science (New York, N.Y.)
|June 5, 2004
PubMed
まとめ

嗅覚球の球の成熟は,特定の発達期間の感覚情報に依存する. 初期段階の異質なグルメリウムは,通常は一時的なもので,感覚の入力が遮断されたときに持続し,神経細胞の生存期間が長くなることを示唆しています.

科学分野:

  • 神経科学は神経科学である.
  • 嗅覚システム開発
  • 感覚処理は,感覚を処理するプロセスです.

背景:

  • 嗅覚エピテリウムから嗅覚球球への軸突の突出は,グルメリウムと呼ばれる構造を形成する.
  • グローメルーラの組織は,嗅覚感覚ニューロンによって発現される特定の嗅覚受容体に基づいています.
  • これらの球球の成熟過程は複雑で,完全に理解されていません.

研究 の 目的:

  • 異なる匂い受容体に対する球成熟の時間的動態を調査する.
  • 球の発達における感覚入力と敏感期間の役割を決定する.
  • 感覚的剥奪の条件下で異質な球構造の持続性を調査する.

主な方法:

  • 嗅覚システムの発達を研究するために,遺伝子標的のマウスを利用した.
  • 感覚的欠乏を誘発するために,一方的なナリスの閉塞によって,操作された感覚の入力.
  • 異なる発達段階と実験条件下で,球組織と神経細胞の生存を分析した.

主要な成果:

  • グローメルーラの成熟は,異なる,しかし類似した,匂い受容体に対して,明確な時間経過を示します.
  • 特定の敏感期間の感覚インプットは,適切な球成熟のために非常に重要です.

さらに関連する動画

Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period
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Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period

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Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice
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Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice

Published on: October 3, 2025

関連する実験動画

Last Updated: Jul 11, 2026

A Wind Tunnel for Odor Mediated Insect Behavioural Assays
05:25

A Wind Tunnel for Odor Mediated Insect Behavioural Assays

Published on: November 30, 2018

Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period
07:13

Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period

Published on: March 1, 2024

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice
09:30

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice

Published on: October 3, 2025

  • 異なる受容体を発現するニューロンからの軸索が収束する異質なグルメリウムは,通常,年齢とともに消失します.
  • 片側ナリスの閉塞は,成人のマウスではこれらの異質なグルメリウムの持続につながります.
  • 嗅覚感覚ニューロンの長期生存は,異質なグルメリウムの持続に寄与する可能性があります.
  • 結論:

    • 嗅覚球球の発達は,感覚インプットのタイミングによって影響されるダイナミックなプロセスです.
    • 嗅覚球の回路の正しい組織化のために,開発中に特定の敏感な期間が存在します.
    • 感覚経験は,異常な軸索の接続を排除し,球構造を精製する上で重要な役割を果たします.
    • 感覚的欠乏下で異質なグルメリウムの持続は,正常な回路の精錬が感覚的経験に依存することを強調し,神経生存機構の役割を示唆する.