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Updated: Jul 6, 2026

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation
08:47

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation

Published on: March 5, 2018

カスパーゼ-1アダプターASCとIPAFによる炎症体の微分活性化

Sanjeev Mariathasan1, Kim Newton, Denise M Monack

  • 1Molecular Oncology Department, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.

Nature
|June 11, 2004
PubMed
まとめ

アダプタASCは,炎症体の活性化およびその後のIL-1β/IL-18の成熟に不可欠です. Ipafは特に細胞内病原体によるカスパース-1の活性化を媒介し,炎症と細胞死経路に影響を与えます.

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