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Updated: Jul 16, 2026

The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli
10:41

The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli

Published on: January 13, 2013

エポチロンの前駆体誘導生物合成は,Escherichia coliで行われる

Christopher N Boddy1, Kinya Hotta, Martha Lovato Tse

  • 1Departments of Chemical Engineering, Chemistry, and Biochemistry, Stanford University, Stanford, California 94305-5025, USA.

Journal of the American Chemical Society
|June 17, 2004
PubMed
まとめ

エンジニアリングされたバクテリアは,現在,前駆体誘導生物合成法を使用して,抗癌薬エポチロンCを生産することができます. このアプローチは,化学合成と酵素処理を組み合わせて,効率的な薬剤生産を実現します.

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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü602809:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

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