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From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
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LARGEによる分子認識は,機能的なディストログリカン発現に不可欠です

Motoi Kanagawa1, Fumiaki Saito, Stefan Kunz

  • 1Howard Hughes Medical Institute, Department of Physiology and Biophysics, The University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, Iowa 52242, USA.

Cell
|June 24, 2004
PubMed
まとめ

LARGEによるディストログリカンの分子認識は,機能的なグリコシル化,筋肉および中枢神経系疾患の予防に不可欠です. この酵素基板相互作用は,筋肉の健康に不可欠な成熟した,機能的なディストログリカンへの経路を開始します.

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Glucose Absorption Into the Small Intestine01:26

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Complex carbohydrates consumed cannot be absorbed into the small intestine in their original form. First, they must be hydrolyzed to a monosaccharide form such as glucose or galactose. These monosaccharides are then transported across the intestinal membrane and into the blood via transcellular transport. The intestinal epithelial cells allow the movement of these monosaccharides with a defined 'entry' through membrane transporter proteins present on their apical membrane and 'exit' via the...