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心理的ストレスに対する血圧の反応性は,CARDIA研究で高血圧を予測しています
Karen A Matthews1, Charles R Katholi, Heather McCreath
1University of Pittsburgh, 3811 O'Hara St, Pittsburgh, PA, USA. matthewska@upmc.edu
Circulation
|June 24, 2004
まとめ
若い成人の心理的ストレス中に頻繁に大きく血圧 (BP) が上昇することは,将来の高血圧を予測します. この発見は,高血圧を発症させる危険因子として,ストレス誘発のBP反応性を強調しています.
科学分野:
- 心血管の健康について
- 精神生理学 精神生理学とは
- 高血圧の研究 高血圧の研究
背景:
- 心理的ストレス中に頻繁に,大きな血圧 (BP) が上昇すると,本質的な高血圧を発症するリスクが増加する可能性があると,長年の仮説が示唆しています.
- この研究では,心理的ストレス中のBP変化が,若い成人における高血圧の発生率を予測するかどうかを調査しています.
研究 の 目的:
- 心理的ストレスに対する血圧反応が,若年成人におけるインシデント高血圧を予測するかどうかを判断する.
- 様々なストレスタスクに対する高血圧の反応と,13年間にわたる高血圧の発達との関連を調べる.
主な方法:
- 生存分析は,13年間にわたるCARDIA研究から4100人以上の正常血圧の男女 (18-30歳) の高血圧状態を予測するために使用されました.
- 3つの心理的な挑戦 (冷圧器,星を追跡,ビデオゲーム) に対する血圧の反応が測定されました.
- 高血圧は,抗高血圧薬の使用またはBP≥140/90mmHgとして定義されました.
主要な成果:
- 3つの心理的なタスクに対する高血圧の反応は,共変数調整後,高血圧の早期発症 (P<0,0001~<0.01) と有意に関連していた.
- 冷圧器のタスクに対するシストリックBP反応の効果は,女性および白人個人に顕著でした.
- ビデオゲームタスクに対するダイアストリックBP応答の効果は,男性において有意であった.
結論:
- 心理的ストレスに対する血圧反応が著しく高い若い成人は,中年期までに高血圧を発症するリスクが高くなります.
- ストレスに起因する血圧反応は,将来の高血圧の潜在的予測因子である.
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