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Updated: Jul 23, 2026

Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations
13:09

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Published on: January 4, 2018

酸塩化物からの有機ニトリル: (O) CLの同価N交換反応で,タングステンニトリド複合体が媒介する

Christopher R Clough1, Jane B Greco, Joshua S Figueroa

  • 1Department of Chemistry, Massachusetts Institutes of Technology, 77 Massachusetts Avenue, Room 2-227, Cambridge, Massachusetts 02139-4307, USA.

Journal of the American Chemical Society
|June 24, 2004
PubMed
まとめ

トングステン・ニトリド複合体NW(N[i-Pr]Ar) 3はピバオイル塩化物と反応して97%の産出率でニトリルを形成する. この研究は,新型の酸ナトリドおよびアシリミド複合体の合成と反応性を詳細に説明しています.

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Nucleophilic Substitution Reactions

Historical perspective
In 1896, the German chemist Paul Walden discovered that he could interconvert pure enantiomeric (+) and (-) malic acids through a series of reactions. This conversion suggested the involvement of optical inversion during the substitution reaction. Further, in 1930, Sir Christopher Ingold described for the first time two different forms of nucleophilic substitution reactions, which are known as SN1 (nucleophilic substitution unimolecular) and SN2 (nucleophilic substitution...
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