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Updated: Aug 6, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

転写因子NF-kappaBの活性化には,IkappaBキナーゼ調節サブユニットであるELKSが必要です

Jeanette L Ducut Sigala1, Virginie Bottero, David B Young

  • 1Salk Institute for Biological Sciences, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|June 26, 2004
PubMed
まとめ

研究者は,イカッパBキナーゼ (IKK) 複合体の重要なレギュレータとしてELKSを特定しました. ELKSを静止すると,NF-kappaBの標的遺伝子発現を阻害し,炎症とアポトーシスに影響を与えます.

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Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO13:02

Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO

Published on: December 28, 2019

NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells10:57

NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells

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