関連する実験動画

Updated: Jul 22, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

タンパク質とDNAのインターフェースでの適応性:非自然な核酸を認識するために刻まれたホメオドメインを再設計する

Matthew D Simon1, Kevan M Shokat

  • 1Department of Chemistry, University of California, Berkeley, CA 94720, USA.

Journal of the American Chemical Society
|July 1, 2004
PubMed
まとめ

研究者たちは,不自然なDNA核酸を認識するために,ホメオドメインのタンパク質を設計した. このタンパク質-DNAインターフェースの適応は,自然相互作用に類似して,改変されたDNAに対する高い親和性と特異性を示しています.

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Homologous Recombination

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