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Updated: Aug 1, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

形状変化した核酸化物 - - フレキシマー - - の形状特性

Matjaz Polak1, Katherine L Seley, Janez Plavec

  • 1Slovenian NMR Center, National Institute of Chemistry, Hajdrihova 19, POB 660, SI-1001 Ljubljana, Slovenia.

Journal of the American Chemical Society
|July 1, 2004
PubMed
まとめ

フレキシマーヌクレオシドは,柔軟な核塩基により,抗コンファメーションとノース型糖のコンファメーションが増加している. これらの発見は,柔軟な結合部位を標的とした形状模倣核酸化物を設計する上で極めて重要です.

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