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Updated: Jul 14, 2026

Modeling Myotonic Dystrophy 1 in C2C12 Myoblast Cells
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Modeling Myotonic Dystrophy 1 in C2C12 Myoblast Cells

Published on: July 29, 2016

Antisense c-myb オリゴヌクレオチドは,内臓動脈の滑らかな筋肉細胞の蓄積を vivo で抑制する

M Simons1, E R Edelman, J L DeKeyser

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.

Nature
|September 3, 1992
PubMed
まとめ

合成のアンチセンセスのオリゴヌクレオチドは,今,in vivoで局所的に投与することができます. このアプローチは,ネズミの動脈における滑らかな筋肉細胞の蓄積を成功裏に抑制し,潜在的な心臓血管治療法を強調しました.

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