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無料エネルギーの景観の荒れを定量化:エントロピー的なボトルネックとタンパク質の折り畳み率

Leslie L Chavez1, José N Onuchic, Cecilia Clementi

  • 1Center for Theoretical Biological Physics and Department of Physics, University of California at San Diego, La Jolla, California 92093, USA.

Journal of the American Chemical Society
|July 9, 2004
PubMed
まとめ

この研究では,タンパク質の折り畳み速度とメカニズムを説明するために,トポロジカル・ディスクリプタを導入します. 構成エントロピーの異質性を定量化することは,実験的に観察された折り畳みダイナミクスの単純な理論的基礎を提供します.

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