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Updated: Jun 23, 2026

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
10:21

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Published on: June 14, 2016

拡張性心筋症候群の患者におけるチチンの発現変化,心筋硬化,左心室機能の変化

Sherif F Nagueh1, Gopi Shah, Yiming Wu

  • 1Section of Cardiology, Department of Medicine, Baylor College of Medicine, 6550 Fannin, SM-1256, Houston, TX 77030-2717, USA. sherifn@bcm.tmc.edu

Circulation
|July 9, 2004
PubMed
まとめ

心不全では,巨大なタンパク質のチチンは,より適合性の高いN2BA同型にシフトし,心筋硬直を軽減し,静脈充填と運動耐性に影響を及ぼします. これは,変化したチチンの発現が拡張性心筋病の鍵であることを示唆しています.

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