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3'-RNA処理因子によるRNAポリメラーゼIIカルボキシ末端ドメインの認識

Anton Meinhart1, Patrick Cramer

  • 1Department of Chemistry and Biochemistry, Gene Center, University of Munich, 81377 Munich, Germany.

Nature
|July 9, 2004
PubMed
まとめ

RNAポリメラーゼIIのカルボキシ末端領域 (CTD) はリン酸化を受け,RNA処理のためにPcf11のようなタンパク質と相互作用することを可能にします. この研究は,この相互作用の構造的基礎を明らかにし,CTDダイナミクスのベータスパイラルモデルを提案しています.

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