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Updated: Jun 29, 2026

Progressive-ratio Responding for Palatable High-fat and High-sugar Food in Mice
11:16

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Published on: May 3, 2012

生理学:腸内ホルモンPYY3-36は,ネズミの食物摂取量を減少させるのか?

M Tschöp1, T R Castañeda, H G Joost

  • 1Department of Psychiatry, University of Cincinnati Genome Research Institute, Cincinnati, Ohio 45237, USA. tschoemh@ucmail.uc.edu

Nature
|July 13, 2004
PubMed
まとめ

潜在的肥満療法である腸内ホルモンPYY3-36に関する研究の複製は失敗した. これらの発見は,抗肥満治療のためのPYY3-36の有効性を疑問視しています.

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Hormonal Regulation01:40

Hormonal Regulation

Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...