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Updated: Jul 15, 2026

Purification of Mouse Brain Vessels
07:32

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Published on: November 10, 2015

トリプトファンヒドロキシラーゼ-2は,脳のセロトニン合成を制御する

Xiaodong Zhang1, Jean-Martin Beaulieu, Tatyana D Sotnikova

  • 1Howard Hughes Medical Institute Laboratory, Department of Cell Biology, and Center for Models of Human Disease, Institute for Genome Sciences and Policy, Box 3287, Duke University Medical Center, Durham, NC 27710, USA.

Science (New York, N.Y.)
|July 13, 2004
PubMed
まとめ

トリプトファンヒドロキシラーゼ-2 (Tph2) の遺伝的変異により,脳のセロトニンレベルが低下する. この発見は,セロトニン合成の調節におけるTph2の重要な役割を強調し,精神疾患の研究に影響を与えています.

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