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Updated: Jul 8, 2026

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
19:16

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

Published on: March 17, 2010

フラタキシンは鉄のチャペロンタンパク質として作用し,ミトコンドリアのアコニテーゼ活性を調節する

Anne-Laure Bulteau1, Heather A O'Neill, Mary Claire Kennedy

  • 1Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH, USA.

Science (New York, N.Y.)
|July 13, 2004
PubMed
まとめ

フラタキシン (Frataxin) は,鉄のチャペロンであり,鉄と硫黄のクラスタを安定させることで,アコニテーゼの活動を保護する. この相互作用は,退行性疾患におけるミトコンドリア機能障害の予防に極めて重要です.

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