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Updated: Jul 25, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Published on: June 20, 2014

リチウム触媒化ヒドロキシドがメチルリン酸塩の炭素原子に攻撃する

Richard Wolfenden1, Frances Zhao

  • 1Department of Biochemistry & Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599, USA. water@med.unc.edu

Journal of the American Chemical Society
|July 15, 2004
PubMed
まとめ

リン酸エステルの水解は遅いですが,メチルリン酸にヒドロキシド攻撃を含む新しい反応経路により,より速い裂解法が提供されます. この生体模倣反応の速度は,ヒドロキシドリチウム濃度に依存する.

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Nucleophilic Addition to the Carbonyl Group: General Mechanism

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Enolate Mechanism Conventions

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