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Updated: Jul 11, 2026

RNA Interference in Aquatic Beetles as a Powerful Tool for Manipulating Gene Expression at Specific Developmental Time Points
08:55

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アルゴナウト2は哺乳類のRNAiの触媒エンジンである

Jidong Liu1, Michelle A Carmell, Fabiola V Rivas

  • 1Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

Science (New York, N.Y.)
|July 31, 2004
PubMed
まとめ

遺伝子サイレンシングは,RNA誘発サイレンシング複合体 (RISC) を使用しています. Argonaute2タンパク質は,マウス発育とRNA干渉反応に不可欠な,メッセンジャーRNAの分裂に不可欠な"スライサー"活性を提供します.

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RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
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RNA Interference01:23

RNA Interference

RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...
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