関連する実験動画

Updated: Jul 14, 2026

Rapid Generation of Amyloid from Native Proteins In vitro
05:48

Rapid Generation of Amyloid from Native Proteins In vitro

Published on: December 5, 2013

シアノゲンブロミド割れは,発現したタンパク質とグリコプロテインの結合に適した断片を生成します

Derek Macmillan1, Lubna Arham

  • 1School of Chemistry, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh, Scotland, UK. derek.macmillan@ed.ac.uk

Journal of the American Chemical Society
|August 5, 2004
PubMed
まとめ

シアノゲンブロミドは,発現タンパク質結合 (EPL) のためのN端システインタンパク質断片を効率的に生成します. この方法は,タンパク質の断片をペプチドまたはグリコペプチド模倣物質と結合させ,半合成グリコプロテイン治療薬の作成を可能にします.

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