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Updated: Jul 16, 2026

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
10:37

Comparing the Affinity of GTPase-binding Proteins using Competition Assays

Published on: October 8, 2015

グアニジニウムグループは,フォスフォリル転移反応における一般酸の触媒として作用する:モデルシステム上の2プロトン在庫

Anna M Piatek1, Mark Gray, Eric V Anslyn

  • 1Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712, USA.

Journal of the American Chemical Society
|August 12, 2004
PubMed
まとめ

この研究は,モデル化合物におけるフォスフォディエステル分裂/トランスエステル化の速度を決定するステップで2つの陽子が移動することを明らかにしています. これは,グアニジニウム基を含む一般的な酸触媒機構を示唆しています.

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