S6K1の欠如は,年齢および食事による肥満から保護し,同時にインスリン感受性を高めます

Sung Hee Um1, Francesca Frigerio, Mitsuhiro Watanabe

  • 1Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.

Nature
|August 13, 2004
PubMed
まとめ

S6キナーゼ1 (S6K1) 欠乏症は,脂肪の分解を促進することによって,肥満から保護します. しかし,S6K1はインスリンシグナル伝達を否定的に調節し,特に脂肪が多い状態では,糖尿病の新たな治療標的を提供している.

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