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John M Antos1, Matthew B Francis

  • 1Department of Chemistry, University of California, Berkeley, CA 94720-1460, USA.

まとめ

新しいロジウム触媒反応により,水溶液中のビニル置換ダイアゾ化合物を用いて,タンパク質内のトリプトファンの残留物を選択的に改変することができます. この方法は,タンパク質濃度が低い場合でも有効であり,ミオグロビンにおけるヘム結合などのタンパク質機能を保ちます.

関連する概念動画

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