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Updated: May 7, 2026

Quantifying Agonist Activity at G Protein-coupled Receptors
11:45

Quantifying Agonist Activity at G Protein-coupled Receptors

Published on: December 26, 2011

チャンネルゲーティングへのアゴニスト結合のカップリングは,イオンチャネルに結合したACH結合タンパク質に結合します

Cecilia Bouzat1, Fernanda Gumilar, Guillermo Spitzmaul

  • 1Instituto de Investigaciones Bioquimicas, UNS-CONICET, Bahia Blanca 8000, Argentina.

Nature
|August 20, 2004
PubMed
まとめ

研究者は,神経伝達物質受容体がアゴニスト結合とイオン孔開きをどのように結びつけるかを調査しました. 結合領域と毛孔領域の構造的互換性は,相互に作用するループによって媒介される,機能的な結合に不可欠であることを発見しました.

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